QUESTIONS A-03

Pharmacology Category:

1. In synaptic neurotransmission, which of the following ions plays a significant role in neurotransmitter release?
a. Sodium
b. Potassium
c. Magnesium
d. Calcium
e. Chloride

2. The primary mechanism of neurotransmitter release is accomplished by what process?
a. Diffusion
b. Carrier-mediated
c. Active transport
d. Facilitated transport
e. Exocytosis

3. What is the amino acid precursor in the synthesis of catecholamines?
a. Phenylalanin
b. Glycerine
c. Tyrosine
d. tryptamine
e. Glutamic acid

4. In the biosynthesis of Norepinephrine, what step is considered as rate-limiting?
a. Active uptake of tyrosine
b. Conversion of tyrosine to dihydroxyphenylalanine
c. Conversion of DOPA to Dopamine
d. Uptake of Dopamine in presynaptic storage vesicles
e. Conversion of Norepinephrine to Epinephrine

5. Which of the following substances exert a negative feedback control on Tyrosine Hydroxylase which serves as the mechanism for moment-to-moment regulation of the rate of catecholamine synthesis?
a. Dopamine
b. Acetylcholine
c. DOPA
d. Epinephrine
e. Norepinephrine