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Sunday, February 10, 2013

Characteristics of Insulin Preparation

Pharmacokinetic Type
Species
Peak in hours
Duration in hours
Ultra-fast-acting
Insulin lispro, aspart, glulisine

Human, modified

0.25-0.50

3.0-4.0
Fast-acting
Insulin injection USP (regular, crystalline zinc)

Human, pork

0.50-3.0

5.0-7.0
Intermediate-acting
NPH Insulin (isophane insulin suspension USP)
Lente Insulin (insulin zinc suspension USP)

Human, pork

8.0-12.0

18.0-24.0
Human, pork
8.0-12.0
18.0-24.0
Long-acting
Untralente (insulin zinc suspension extended USP)
Protamine Zinc insulin

Human

8.0-16.0

18.0-28.0
Human
8.0-16.0
18.0-28.0
Untra-long-acting
Insulin glargine

Human, modified

No peak

>24.0
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