IPP REVENUE HITS

Sunday, December 21, 2014

Pharmaceutical Juices

Juices are expressed juices prepared from fresh ripe fruits, used in syrups which are employed as vehicles. Freshly expressed juices are preserved with benzoic acid allowed to stand at room temperature for several days until all pectin naturally present are destroyed by enzymatic action (TEST: Filter juice yields a clear solution with alcohol). Pectin if present will cause precipitation in the final syrup. Although artificial flavors lack flavor of the natural fruit juice, but since they are more stable and easier to incorporate into the final pharmaceutical form they have replaced man of the natural fruit juices.
Juices expressed from fresh plants and evaporated were formerly known as “Inspissated Juices”.

Examples of Juices:

Cherry Juice USP

Preparation:
Coarsely crush the washed, stemmed, unpitted sour cherries (Prunus Cerasus Linne (Fam. Rosaceae)) in a grinder to break the pits but not mash the kernels. Dissolve 0.1% of benzoic acid in the mixture, allow to stand at room temperature (possible for several days) until a small portion of the filtered juice remains clear when mixed with ½ of its volume of alcohol and the resulting solution remains clear for 30 minutes. Pressed the juice and filter.

Possible Uses: Used to prepare cherry syrup.



Raspberry Juice USP

Preparation:
Express the juice from the washed, well-drained, fresh ripe red raspberries (varieties of Rubrus idaeus Linne or of Rubrus stringosus Michaus (Fam. Rosaceae). Dissolve 0.1% of benzoic acid in the juice, allow to stand at room temperature (for several days) until a small portion of the filtered juice produces a clear solution when mixed with ½ of its volume of alcohol, the solution remains clear for at least 30 minutes. Strain the juice and filter, if necessary.

Possible Uses: Preparation of Raspberry Syrup.


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