IPP REVENUE HITS

Saturday, March 28, 2015

Best Lotion in the Market



Beauty products are everywhere! Whether it is cosmetic, whitening or cleansing products, which user can choose from and satisfy her needs. Lotion is a beauty product that is applied to skin, which benefits the user. Lotion can be in medicinal form sometimes. In fact before lotion became popular as a beauty product it was known years and years ago as a drug. Lotion has many uses. It can be used for dry skin problem, as whitening product, as moisturizer, sunblock, nourishment for the skin or even as discussed above as medicine.


Examples of Lotions Commercially Available

Skin White Lotions
·         SkinWhite Advanced Whitening Lotion Glutathione + Vitamin C SPF 20
·         SkinWhite Classic Whitening Lotion SPF 20
·         SkinWhite Classic Whitening Lotion Hydrating with Lycopene
·         SkinWhite Advanced Whitening Lotion PowerWhitening SPF 20
·         SkinWhite Classic Whitening Lotion SPF 10
·         SkinWhite Naturals Whitening Lotion Papaya Milk SPF 10
·         SkinWhite Advanced Whitening Lotion Glutathione + Vitamin C SPF 20
·         SkinWhite Advanced Whitening Lotion Kojic Acid SPF 20

Nivea Lotions
·         Nivea Express Hydration Lotion - formula with HYDRA IQ technology
·         Nivea In Shower Body Lotion
·         In Shower Body Lotion - Enriched with Sea Minerals
·         Nivea UV Protect - Vitamin E and Hydra IQ
·         Nivea Firming Body Lotion Q10 Plus
·         Nivea Whitening Cell Repair & Protect for Men - Hydra IQ, Vitamin E and White Bio-Active Formula
·         Nivea Revitalizing Body Lotion – Vitamin E

Dove Lotion
·         Dove Cream Oil Shea Butter Body Lotion
·         Dove Cream Oil Intensive Body Lotion

Vaseline Lotions
·         Vaseline Intensive Care Essential Healing Lotion
·         Vaseline Intensive Care Advanced Repair Fragrance Free Lotion
·         Vaseline Intensive Care Advanced Repair Lightly Scented Lotion
·         Vaseline Intensive Care Aloe Soothe Lotion
·         Vaseline Intensive Care Cocoa Radiant Lotion
·         Vaseline Intensive Care Cocoa  Radiant Deep Conditioning Cream
·         Vaseline Intensive Care Cocoa Radiant Body Gel Oil

Jergens Lotions
·         Jergens Shea Beauty Oil
·         Jergens Shea Butter Deep Conditioning Moisturizer
·         Jergens Ultra Healing Extra Dry Skin Moisturizer
·         Jergens Original Scent Dry Skin Moisturizer
·         Jergens Daily Moisture Dry Skin Moisturizer
·         Jergens Daily Moisture Fragrance Free Dry Skin Moisturizer
·         Jergens Skin Firming Toning Moisturizer
·         Jergens Soothing Aloe Refreshing Moisturizer
·         Jergens Overnight Repair Nightly Restoring Moisturizer
·         Jergens Age Defying Multi-vitamin Moisturizer
·         Jergens Skin Smoothing Gentle Exfoliating Moisturizer

GlutaWhite C Lotion – Papaya and Gluthathione

Silka Papaya Skin Whitening Lotion



Advantage of Lotion:
1. It can moisturize dry skin which helps to retain moisture of the skin. It prevents the skin from scaling and cracking.
2. It can nourish the skin with incorporation of vitamins within it.
3. Prevents the harmful UV rays from the sun to penetrate the skin by absorbing or refracting the rays with the help of opacifying agent.
4. It can help to whiten the skin as the resulting effect of sunscreen.
5. Use to treat some skin disease.
6. Easily to apply.


Disadvantage:
1. Oily, sticky and uncomfortable sometimes, especially when skin perspires much.
2. Allergies can form.
3. Expensive and easily to consume.
4. If application does not follow, problems may occur.
5. Frequent reapplying for use as sunblock.

Types of Lotion
1. Moisturizer Lotion – Use to help moisturize dry skin. It is much needed by individuals living in cold climate areas. As lotion moisturizes the skin, the scaling and cracking can be prevented. Thus, skin comes back to its firmness which gives smooth and soft feeling. Lotions are added with aloe vera extract, vitamin E, glycerin, chamomile extract and other herbal extracts as moisturizing agent.

2. Sunblock or SPF Lotion – it is a lotion for protecting the skin from damaging sun’s UV rays. Lotion is added with opacifying agent or agents that can reflect or absorption UV rays. It is a supplementary help to melanin which is the sun protecting cells in the skin. Melanin is responsible for darkening of skin and dark spots, moreover, UVA and UVB are responsible for abnormal skin aging, wrinkles and etc. Lotion can prevent the formation of skin cancer when use regularly. Examples of opacifying or sunscreen agents are tinanium oxide, zinc oxide, octocrylene, avovenzole and etc. The higher the SPF number is the higher the protection you get against the UV.

3. Whitening Lotion – Whitening effect of lotions can be benefited from the use of sunblock. As a resulting protection and non-penetration of UV rays in the skin, the skin does not need to produce much melanin that causes the dark pigmentation of the skin. Daily and frequently use of lotion is required to achieve one step skin tone level at a time. Some lotions are augmented with glutathione for better skin tone improvement.

4. Nourishment Lotion – Skin can be nourished through the application of lotion. Lotion can be incorporated with essential vitamins and supplements that are mostly needed by the skin. Such vitamins are Vitamin E, Vitamin A, Vitamin B3 and B5 and others to support skin needs.

5. Medicinal / Insect Repellant Lotion – Lotion which incorporation of medicinal drugs or chemical agents to treat such skin infection or disease or repel insects. Example of this drug is the Kwell lotion that contains permethrin as drug agent, which uses to treat skin and hair lice, and insect repellant such as Off lotion. But these lotions come with certain percentage or strength of the active agent to treat skin or repel mosquitoes.

Consideration of Choosing the Best Lotion for you:
1. It meets your needs and problem.
2. Available and cost-effective.
3. Beneficial and not causing allergies.
4. Quality of production has met the international standards.
5. Tests are done and clinically proven.
6. Manufacturer’s reputation is good.
7. Registered by FDA or other government regulating agencies.
8. Hypo-allergenic or non-comedogenic.
9. Easy to use and apply.
10. Promise results should be true and achievable.
11. Should not be too oily and sticky. Instead the lotion should be water base and easily absorbed by skin.

Friday, March 27, 2015

Pharmaceutical Lotion



Lotions are usually liquid suspensions or dispersions intended for external application to the body. They may be prepared by:

(1) Triturating the ingredients to a smooth paste and then cautiously adding the remaining liquid phase or in larger quantities by the use of high-speed mixers or homogenizers. Classical example is the Calamine Lotion, which consists of finely powdered insoluble solids held in more or less permanent suspension by the presence of suspending agents and/or surface active agents.

(2) By chemical interaction in the liquid. Example – White Lotion which must be freshly prepared and does not contain a suspending agent. The second type of lotion recognized by the USP XVII is the O/W type stabilized by a surface active agent. Example of this is Benzyl Benzoate Lotion.

(3) Some Lotions are clear solutions and in fact, the active ingredients of one official lotion, Dimethisoqun Hydrochloride Lotion, is a water soluble substance.

Lotions are usually applied without friction. The insoluble matter should be finely divided as particles approaching colloidal dimensions are more soothing to inflamed areas and are more effective in contact with infected surfaces. A wide variety of ingredients may be added to the preparation to produce better dispersion or to accentuate the cooling, soothing, drying, or protective properties of the lotion. A good example of suspending agent is bentonite. Methylcellulose or sodium carboxymethylcellulose will localize and hold the active ingredient in contact with affected site. A formulation containing glycerin will keep the skin moist for a considerable period of time. Addition of alcohol to the formula will accentuate the drying and cooling effects.

Dermatologist frequently prescribe lotions containing anesthetics, antiseptic, astringents, germicides, protective or screening agents, to be used in treating and preventing various types of skin disease and dermatitis. Antihistamines, benzocaine, calamine, resorcin, steroids, sulfur, zinc oxide, and zirconium oxide are common ingredients in unofficial lotions.

Lotions tend to separate or stratify on long standing, so a “shake well” label is required for them. All lotions should be labeled “For External Use Only”.


Preparations of Lotions

Benzyl Benzoate Lotion, USP, BP

Other Names: Lotio Benzylis Benzoatis; Benzyl Benzoate Application.

Formula:
Benzyl Benzoate              250ml
Triethanolamine                  5g
Oleic Acid                          20g
Water                                750ml
          To make about      1000ml

Preparation:
Mix together the triethanolamine and oleic acid add the benzyl benzoate and mix well. Transfer the mixture to a suitable container of about 2000ml capacity, add 250ml of water and shake thoroughly. Add the remaining 500ml of water and shake again.

Uses: Scabicide. It is applied with a brush after the entire body has been thoroughly scrubbed with soft soap and hot water. A second coating is applied when the first is dry and the lotion is left on the body for 24 hours. Then the body is again bathe thoroughly and dressed in clean clothes.

Application: Adults require from 120 – 180ml. Children require from 60 – 90ml.

Caution: Do not apply to the face!


Calamine Lotion, USP

Other Name: Lotio Calaminae

Formula:
Calamine                                               80g
Zinc Oxide                                            80g
Glycerin                                               20ml
Bentonite Magma                                20ml
Calcium Hydroxide Solution q.s.     ________
                 To make                            1000ml

Preparation:
Dilute the bentonite magma with an equal volume of calcium hydroxide solution. Mix the powders intimately with the glycerin and about 100ml of the dilute magma, triturating until smooth, uniform paste is formed. Gradually incorporate the remainder of the diluted magma. Finally add enough calcium hydroxide solution to make 1000ml and shake well.
Uses: Astringent and protective.

Note: Shake lotions thoroughly before dispensing. If a more viscous consistency is desired, the quantity of bentonite magma may be increased to not more than 400ml.



Phenolated Calamine Lotion, USP

Other Names: Lotion Calaminae Phenolata; Lotion Calaminae Composita; Compound Calamine Lotion.

Formula:
Liquefied Phenol             10ml
Calamine Lotion             990ml
              To make           1000ml

Preparation:
Mix the ingredients thoroughly.

Uses: Astringent and protective for skin diseases. Shake well before using.


White Lotion, USP

Other Names: Lotio Alba; Lotio Sulfurata

Formula:
Zinc Sulfate                         40g
Sulfurated Potash                40g
Purified Water, q.s.       __________
           To make                 1000ml

Preparation:
Dissolve the zinc sulfate and the sulfurated potash separately, each in 450ml of purified water, and filter each solution. Add slowly the sulfurated potash solution to the zinc sulfate solution with constant stirring. Then add sufficient amount of purified water and mix.

Uses: Topically as astringent and protective.

Note: Lotion should be freshly prepared and shaken thoroughly before dispensing.

The lotion is a result of the chemical reaction between zinc sulfate and sulfurated potash and can be illustrated as follows:
 

ZnSO4       +      K2S3                            K2SO4           +         ZnS           +      2 S
Zinc Sulfate                Sulfurated Potash            Potassium Sulfate       Zinc Sulfate           Sulfur

The sulfurated potash solution should be added to zinc sulfate solution with constant stirring. This ensures a fine dispersion of the insoluble precipitates, upon long standing tends to become lumpy and yellowish in color.


Thursday, March 26, 2015

Pharmaceutical Gels



Gels are suspensions, in a water medium, of insoluble drugs in hydrated form wherein the particle size approaches or attains colloidal dimensions. In addition to the active ingredients, gels may contain peppermint oil, glycerin, sorbitol, sucrose, saccharin and various preservatives. This list of ingredients is not all-inclusive but is based on information found in the monographs of official preparations. Generally, if gels are left undisturbed for some time, they may become semisolid or gelatinous, with some small amounts of water separating on standing.


Preparations of Gels

1. Aluminum Hydroxide Gel, USP, BP

Other Names: Gelatum Alumini Hydroxidi; Colloidal Aluminum Hydroxide; Alugel; Amphogel; Ce-lu-gel; Cremalin; Fluagel; Hydroxal; Vanogel

Formula:

Ammonium Alum                     800g
Sodium Carbonate                   1000g
Purified Water, q.s.               ­­­­­_________
           To Make                        2000ml

Preparation:
Dissolve the Sodium Carbonate in 4000ml of hot water and filter. Dissolve ammonium alum in 2000ml of hot water and filter in the carbonate solution with constant stirring. Then add 4000ml of hot water and remove all gas. Dilute to 80, 000ml of cold water. Collect and wash the precipitate and suspend it in 2000ml of purified water flavored with 0.01% of peppermint oil and preserve with 0.1% of sodium benzoate. Homogenize the resulting gel.

The principal property desired is a very fine particle size to achieve large surface and thus maximum adsorption capacity.

The preparation may contain peppermint oil, glycerin, sorbitol, sucrose saccharin, or other suitable, flavors and it may contain suitable preservatives in a total amount of exceeding 0.5%.

Uses: Antacid in the treatment of peptic ulcer. The compound is not an adsorbent but reacts chemically to neutralize the gastric contents. It has been used for intestinal toxemia, but more effective agents are available. The major advantage of aluminum hydroxide is that no systemic alkalosis is produced. The disadvantage would be constipation.

Dose: Usual, 10ml four times daily or more.


2. Dried Aluminum Hydroxide Gel, NF, BP

Other Name: Gelatum Alumini Hydroxidi Siccum

Preparation: It is prepared as described under aluminum hydroxide gel, and dried at a low temperature until it has the required amount of Al2O3.

Dose: 390mg, the equivalent of 300mg of Al(OH)3, four times a day.


3. Aluminum Phosphate Gel, NF

Other Names: Gelatum Alumini Phosphatis; Phosphagel

Preparation:
The gel may be prepared by precipitation from a solution of aluminum chloride with a solution of sodium phosphate. The particle size of the precipitate which is an important factor in its absorption, is governed by several factors:
(a) The concentration of the reactants.
(b) The temperature and pH maintained during the process.
(c) The manner of addition of reactants whether the sodium phosphate is added to the aluminum solution, or the reverse. The soluble salts formed in the reaction are removed by washing either by decantation with water, or by dialysis.

It may contain peppermint oil, glycerin, sorbitol, sucrose, saccharin, or other suitable agents for flavoring purposes. It may also contain sodium benzoate, benzoic acid, or other suitable agents and in small amount not exceeding 0.5% as preservative.

Uses: Antacid. It has approximately half the neutralization capacity of aluminum hydroxide gel but has the advantage over the latter of not interfering with the adsorption of phosphate from the intestinal tract.

Dose: Usual, 15ml.

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